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Mechanical irritation of the muscle fibers Localized inflammation supported by increased blood flow Short-term immune response concentrated in the injected arm These factors explain why temporary pain can build as the body processes the vaccine

Muscle twitching may be an adverse effect of drugs like corticosteroids and estrogen

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In the context of trichology and dermatology, it is often referred to as a "signal peptide" because it communicates with cells to stimulate repair and regeneration